The L1 Family of Neural Cell Adhesion Molecules: Old Proteins Performing New Tricks
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The L1 Family of Neural Cell Adhesion Molecules: Old Proteins Performing New Tricks
Michael Hortsch chordate phyla (Figure 2). Subsequently, at some point during early chordate evolution, a further separation into Department of Anatomy and Cell Biology University of Michigan three different L1 subfamilies occurred. As exemplified by the two L1-CAM-type molecules found in zebrafish Ann Arbor, Michigan 48109-0616 (Tongiorgi et al., 1995), additional members of the L1 family migh...
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The formation of neurocircuitry depends on the control of neurite outgrowth that, in turn, can be divided into two processes: nerve growth cone protrusion and neurite extension. It has long been known that the neural cell adhesion molecules L1 and NCAM-180 promote neurite outgrowth, but how they function in growth cones is unclear. We addressed the roles of L1 and NCAM-180 in neurite outgrowth ...
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ژورنال
عنوان ژورنال: Neuron
سال: 1996
ISSN: 0896-6273
DOI: 10.1016/s0896-6273(00)80192-0